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Anti-N-methyl-D-aspar tate receptor encephalitis associated with ovarian teratoma: A case report

Journal: The Greek E-Journal of Perioperative Medicine (Vol.15, No. 1)

Publication Date:

Authors : ; ; ; ; ; ;

Page : 39-45

Keywords : Anti-NMDA encephalitis; ovarian teratoma;

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Abstract

We report a rare case of a young woman with anti-N-Methyl-D-Aspartate receptor (NMDAR) encephalitis, who developed psychiatric symptoms, dyskinesias, hypoventilation, hypersalivation and seizures. Serial analysis of antibodies to NR1/NR2B heteromers of the NMDAR was positive on the patient's serum and cerebrospinal fluid (CSF). Removal of an ovarian teratoma after intravenous immunoglobulin and corticosteroid therapy resulted in a prompt neurological response.

Last modified: 2016-12-04 04:50:48