A Case of Tumor Lysis Syndrome after Docetaxel Administration for Recurrent Ovarian Cancer

Tumor Lysis Syndrome is a rare complication of the treatment of solid malignancies. A 51 year old female developed this condition one week after undergoing docetaxel chemotherapy for progressive, recurrent ovarian cancer. She was diagnosed based on classic laboratory disturbances including increased creatinine, hyperphosphatemia, hypercalcemia, hyperkalemia, and hyperuricemia. The patient was successfully treated with aggressive intravenous hydration, allopurinol, and rasburicase. Although uncommon, clinicians should be aware of this condition so that proper identification occurs and treatment can be implemented promptly.