Asymptomatic Presentation of Mediastinal Actinomycosis in a Pediatric Patient with Acute Lymphoblastic Leukemia
Journal: Journal of Clinical & Medical Case Reports (Vol.2, No. 1)Publication Date: 2015-06-30
Authors : Margaret Andre; Tony Walls; Nadeem Haider; Tristan Charles John Pettit;
Page : 1-3
Keywords : Asymptomatic mediastinal actinomycosis; Thoracic mass; Acute lymphoblastic leukemia;
Abstract
We report a nine year old male with Philadelphia positive Precursor B Acute Lymphoblastic Leukemia who was diagnosed with mediastinal actinomycosis following failed central line placement. The patient had a normal chest X-Ray at diagnosis, had a good response to initial chemotherapy, but subsequently developed a widened mediastinum with vascular compression. The differential diagnosis for this included infection, leukemia relapse, a second malignancy and vascular and congenital abnormalities. Actinomycosis is associated with hematogenous spread and invasion of neighbouring structures, and should be considered in the differential diagnosis of any child with a mediastinal mass.
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