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Asymptomatic Presentation of Mediastinal Actinomycosis in a Pediatric Patient with Acute Lymphoblastic Leukemia

Journal: Journal of Clinical & Medical Case Reports (Vol.2, No. 1)

Publication Date:

Authors : ; ; ; ;

Page : 1-3

Keywords : Asymptomatic mediastinal actinomycosis; Thoracic mass; Acute lymphoblastic leukemia;

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Abstract

We report a nine year old male with Philadelphia positive Precursor B Acute Lymphoblastic Leukemia who was diagnosed with mediastinal actinomycosis following failed central line placement. The patient had a normal chest X-Ray at diagnosis, had a good response to initial chemotherapy, but subsequently developed a widened mediastinum with vascular compression. The differential diagnosis for this included infection, leukemia relapse, a second malignancy and vascular and congenital abnormalities. Actinomycosis is associated with hematogenous spread and invasion of neighbouring structures, and should be considered in the differential diagnosis of any child with a mediastinal mass.

Last modified: 2016-12-12 18:58:34