TO STUDY THE THERMODYNAMIC PARAMETERS OF 5-p-CHLOROPHENYLTHIOCARBAMIDO-1-NAPHTHOL AT DIFFERENT CONCENTRATIONS AND DIFFERENT TEMPERATURES IN 70% ETHANOL-WATER MEDIA

Conductivity play vital role in drug diffusion. Thermodynamic parameters affected by substituent's of drug. Thus recently in laboratory, conductometrically have been investigated thermodynamic parameters of 5-pChlorophenylthiocarbamido-1-naphthol [p-CPTCN] or L3 have been studied at different concentrations in 70% ethanol-water mixture at different temperatures. This work highlights investigation of G, K and ? values. The thermodynamic parameters viz. ΔH, ΔS and ?G for ion pair formation determined from the value of ion association constant at 298K and 303K. This investigation provided valuable information regarding to solute-solvents, solute? solute and solvent-solvent interaction and effect of dilution from conductrometric measurements of 5-pChlorophenyl -thiocarbamido-1-nahthol. Key Words: Thermodynamic parameters, Dissociation constant, 5-p-Chlorophenylthiocarb -amido-1-nahthol.