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THE STATE OF ENDOTHELIAL PROCESSES IN PATIENTS WITH CHRONIC HEART FAILURE UNDER TREATMENT OF INHIBITORS OF RENIN-ANGIOTENSIN SYSTEM
Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.7, No. 7)Publication Date: 2004-04-30
Authors : V.G. Psarheva;
Page : 90-94
Keywords : chronic heart failure; disfunction of endothelium; endothelin-1;
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Abstract
We examined 69 patients with chronic heart failure (HF) caused by ischemic heart disease. It was examined endothelial function such as endothelin-1, cAMP, cGMP and 6-keto-PGF1α contens. It was determined that HF has high endothelin-1 level, wich is most in HF IV functional classes, and has low cGMP level. Enalapril and losartan inhibit the activity of RAAS function.
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