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Experimental study of the activity of the hydrogel against burns with antihypoxant

Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.24, No. 1)

Publication Date:

Authors : ; ; ;

Page : 29-34

Keywords : burn; hydrogel; sodium poly(dihydroxyphenylen)thiosulfonate;

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The article presents the results of an experimental study of the activity of the gel against burns with antihypoxant sodium poly(dihydroxyphenylen)thiosulfonate in a certain spectrum of doses. In the simulation of a thermal burn in male rats established that daily application on the wound once a day one strip of hydrogel with sodium poly(dihydroxyphenylen)thiosulfonate of size 1,5-2 cm with content 15 mg or 20 mg of drug substance provides high speed of epithelialization of wound for 16 days, unlike the control group and the intact, in which the complete healing is observed only at 29 days of the experiment. Applying of strip of cream "D Panthenol" of size 2 cm (the comparison group) provided a wound healing during the 26 days of observation.

Last modified: 2017-01-27 21:09:28