The effect of blood ultrafiltration during cardiopulmonary bypas at the markers of inflammation after cardiac surgery

The aim of this study ? to evaluate the effect of blood ultrafiltration during cardiopulmonary bypass with the primary circuit filling solution hydroxyethyl starch 130/0,4 on the markers of systemic inflammatory response in adult patients undergoing heart valve replacement. Material and methods. The study included 56 patients with cardiac pathology, who underwent heart surgery with cardiopulmonary bypass. Patients were divided into two groups. In both groups to support blood oncotic pressure used in the primary circuit filling it with a solut ion of 6% HES 130/0,4. Patients of the second group before the end of cardiopulmonary bypass was performed ultrafiltration. Results. Established that ultrafiltrationremoves from the circulation of pro-inflammatory cytokines and increases the level of anti-inflammatory IL10. It reduces the number and duration of treatment complications.