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SUBACUTE SCLEROSING PAN ENCEPHALITIS-A CASE REPORT

Journal: University Journal of Medicine and Medical Specialities (Vol.3, No. 2)

Publication Date:

Authors : ;

Page : 163-168

Keywords : SSPE; Measles; Negative myoclonus; EEG; CSF antimeasles antibody titre;

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Abstract

Subacute sclerosing panencephalitis (SSPE) is a rare chronic, progressive demyelinating disease of the Central nervous system (CNS) associated with a chronic non permissive infection of brain tissue with measles virus. The frequency has been estimated at 1 in 100,000 to 500,000 measles cases. We report a 13 year old girl who presented with rapid deterioration of cognition and negative myoclonus involving lower limb and trunk. There is no history of measles or immunisation for measles in the past. The diagnosis of subacute sclerosing pan encephalitis was confirmed provisionally with clinical picture and Electroencephalogram (EEG) studies and later confirmed with cerebrospinal fluid (CSF) studies. We report this case in view of its rare incidence.

Last modified: 2017-02-28 19:50:33