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Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.04, No. 02)

Publication Date:

Authors : ; ; ; ;

Page : 193-207

Keywords : Meganucleus; nucleases; Agrobacterium; Genome; CRISPER/Cas9.;

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The Present Review report contains the information about Genome Editing. In this report genome editing is illustrated at the basic level for better understanding. It contains History of Genome Editing from 1800 to Current day i.e. from concept of DNA till current time. Genome editing is an technique to make every human smarter not our choice, by customizing next generation the way we want it to be like to be look and also the intellectual capacity. In this Concept, the viral Immunity is used to treat untreated diseases by using DNA modification technology. Most common and easy way of Genome editing that is CASPER/Cas9 is highlighted in short and other methods like Meganeucleus, Transcription activator-like effectors nucleases, Zinkfiger nucleus all are described in short. The Report also contains flow charts of Targeted mutagenesis using embryonic stem (ES) cells for better understanding. The review report also contains Genome Editing in not only in Humans but in Plants also. Which will give us better Crop yield with greater quality of food and containing more amount of active ingredients. For plants there are points taken which are, The importance of mutants in gene discovery, Agrobacterium-mediated gene-tagging mutagenesis etc. and also a flow chart of Plant Genome editing using CASPER/Cas9 technique. Now at the last but not the lease, Advantages and Disadvantages of Genome Editing to know that what this technique will give us in future and what it will take away from us. Key Words:Meganucleus,nucleases, Agrobacterium, Genome, CRISPER/Cas9.

Last modified: 2017-03-06 00:56:56