A 21-Year Old Woman with Pheochromocytoma Associated with Hypercalcemia: A Case Report

We experienced a case of Pheochromocytoma (PCC), which was found in a 21-year-old woman with hypercalcemia. The leading symptom was abdominal pain and dysmenorrheal. Large ovarian cyst was diagnosed by ultrasound. During induction anesthesia for ovarian cystectomy, the woman developed tachycardia and severe hypertension. Her familial histories were unremarkable. Laboratory examinations showed hypercalcemia (12.5 mg/dl) which was diagnosed 3 years before her last admission to our hospital. Computed tomography showed a heterogeneous mass measuring 12 cm in the left adrenal gland, which had abnormal uptake with 123-I Metaiodobenzylguanidine scintigraphy (MIBG). Serum/urine catecholamines were highly elevated, and serum PTH was mildly increased. The patient underwent open abdominal surgery with En bloc surgical resection of PCC with left adrenalectomy and ovarian cystectomy. The tumor was histological diagnosed as typical pheochromocytoma. Blood pressure was normal with serum calcium slightly decreased after surgery. She was free of disease postoperatively after 6 months of follow up.