METASTATIC INGUINAL LYMPHADENOPATHY OF UNKNOWN PRIMARY

Malignant Inguinal lymphadenopathy arises from malignant tumours in the skin of lower limbs, the cervix, the uterine body, the ovary, the perineum, the rectum, the anus, and the remaining 1 was metastatic cancer with unknown primary site. Two cases with metastatic squamous cell carcinoma inguinal lymphadenopathy primary undetected with all routine clinical and imaging evaluation underwent FDG PET CT scan and then treated. FDG PET CT scan showed increased uptake in the metastatic inguinal nodes (SUV- 10.58 and 17.2) with no other significant uptake of tracer. Both the patients are treated with external beam radiation to the pelvis including both inguinal regions for 41 Gy with concurrent weekly cisplatin and boosting the inguinal node up to 60 Gy. There was complete response and the patients are on follow up. Metastatic inguinal lymph node squamous cell carcinoma of unknown origin is a rare entity and PET CT scan can be used as a valuable tool for the meticulous search of the primary.