PHYSICAL DEVELOPMENT OF SECOND GENERATION OFFSPRING OF WHITE RATS, OBTAINED FROM MALE RATS WHICH WERE BORN FROM MOTHERS WITH CHOLES-TASIS

Objective. To evaluate fertility of male rats whose gestational period was in mothers' cho-lestasis, and peculiarities of physical development of their offspring. Material and methods. The experiment was performed in 2 groups of sexually mature male and female white rats and their offspring by using somatometric and statistical methods of study. Conclusions. Fertility of first generation males whose gestational period was in mothers' cholestasis is reduced and makes up 42.9% as compared to 100% in the control group. Their second generation offspring has a significant physical retardation as compared to animals in the control group.