ТО THE CONCEPTS OF "INTRAUTERINE INFECTION AND FETAL INFECTION"

Introduction. Currently, along with a low level of infant mortality in our country there persists a high incidence of infections specific for the early neonatal period, among which predominate fetal infections. Infections of the fetus and the newborn infant play a significant role in the development of infectious inflammatory diseases. Aim. The aim of the paper is to specify the concepts of intrauterine infection and fetal infection; to introduce neonatologists, pediatricians, pediatric infectious disease specialists, obstetricians and gynecologists to the variants of transition of intrauterine infection into fetal infection; to consider the issues of pathogenesis, clinical presentation, treatment, diagnosis and prevention of the above infections from current point of view. Material and methods. To achieve the aim, we conducted a review of domestic and foreign literature sources on the problem, which allowed us to generalize the features of clinical and laboratory manifestations of fetal infections as well as to identify the main stages of laboratory diagnostics: antenatal diagnosis, early (preclinical) diagnosis at the time of birth and diagnosis of fetal infection with the appearance of clinical signs. Conclusion. The present article will enable physicians with relevant knowledge and skills to organize for themselves such concepts as intrauterine infection and fetal infection. It will also help them to focus on the pathogenesis, clinical manifestations, diagnostics, treatment and prevention of fetal infections, which in turn may reduce morbidity and mortality from infections specific for the early neonatal period as well as the growth of disability among young children due to this disease.