PHYTOCHEMICAL POTENTIAL, ANTIOXIDANT ACTIVITIES AND ENZYME INHIBITORY PROPERTIES OF CRUDE EXTRACT FROM GISEKIA PHARNACEOIDES LINN (MOLLUGINACEAE)

The present work determine the phytochemical potential, antioxidant activity and enzyme inhibition activities of crude extract of Gisekia Pharnaceoides Linn (Molluginaceae).Total phenolic content (TPC) and total flavonoid content (TFC) of the plant extracts were in the range 5.56 ± 1.30--8.11 ± 1.249 mg gallic acid equivalent/g extract and 4.33 ± 1.003--6.31 ± 0.022 mg rutin equivalent/g extract, respectively. Antioxidant actions of crude extracts were evaluated by 1,1-diphenyl-2-picrylhydrazyl free radical (DPPH). The half-maximal inhibitory concentrations (IC50) of the extracts of tyrosinase and α-glucosidase were expressively higher than the references kojic acid and acarbose, respectively. These results suggest that the plant material possess moderate antioxidant activity and thought-provoking inhibitory action against key enzymes that might be due to the existence of phytoconstituents, thus supporting folkloric use. Keywords: Antioxidant, Phenolic, Flavonoid, Inhibition, Cholinesterase, Tyrosinase, α-Glucosidase, Gisekia Pharnaceoides