FREQUENCY OF NEONATAL HYPERBILIRUBINEMIA AND ITS OUTCOME AFTER TREATMENTJournal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.04, No. 04)
Publication Date: 2017-04-21
Authors : Abdul Rehman Siyal; Khalid Yousuf Memon; Hemandas; Munawar Ali Kalhoro;
Page : 960-964
Keywords : Hyperbilirubinemia; newborn; treatment.;
Objective: The objective of this study was to find out the prevalence and outcome after treatment of in neonatal hyperbilirubinemia. Material & Methods: This descriptive study was conducted in the department of LUMH. Total 558 patients were admitted in the nursery of paeds, out of them 144 had hyperbilirubinemia. All the neonates having hyperbilirubinemia were included in the study after taking verbal informed consent from their parents. All the data was recorded regarding gender, type of treatment received and outcome. Results: Neonatal hyperbilirubinemia was found in 144(20.43%) out of 558 neonates. Males were 77(67.54%) while females were 37(32.45%), with male to female ratio as 2.08:1. Regarding treatment 54% neonates received phototherapy while 46% neonates received exchange transfusion +phototherapy. When neonates were observed for complications of treatment in 2(1.75%) neonates developed anemia those were underwent phototherapy, while among neonates those were given exchange transfusion + phototherapy they developed skin rashes in 2(1.75%) neonates and 2(1.75%) had diarrhea. After treatment 80(70.17%) neonates became improved, 15(13.15%) were discharged on their own wish, 11(9.64%) lost follow up and 08(7.01%) were died. Conclusion: We concluded that neonatal hyperbilirubinemia prevalent as 20.43%. Male newborn were more effective. Phototherapy and exchange transfusion+Phototherapy both are effective treatments for neonatal jaundice with very low rate of complications. Keywords: Hyperbilirubinemia, newborn, treatment.
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