Organophosphate Intoxication Due to Suicidal Intent

Organic phosphorus (OP) intoxication comprises a significant portion of intoxication due to agricultural chemicals. This type of intoxication occurs by oral intake, inhalation or skin contact accidentally during use or due to suicidal intent. It is most commonly observed in males from 15-45 years. OP reversibly inhibits the acetylcholinesterase (AChE) enzyme in the synapses. Symptoms and findings appear 1-2 hours after exposure generally linked to the balance between the nicotinic and muscarinic receptors. Treatment comprises general support treatment, decontamination, prevention of absorption and administration of antidote. In this study we present a case with organophosphate intake by the oral route with suicidal intent. We discuss the precautions necessary for OP intoxication and the clinical monitoring and treatment of this patient in intensive care.