Molecular Mechanism of Resveratrol: A Systematic ReviewJournal: Journal of Pharmacy Research (Vol.11, No. 5)
Publication Date: 2017-05-08
Authors : Bibekananda Meher;
Page : 397-409
Keywords : Anticancer; Antiviral; Apoptosis.Hexosamine pathway.Resveratrol.;
Resveratrol is a naturally occurring compound of therapeutically importance due to its diverse pharmacological action. Resveratrol (RV) posses significant role viral infections, cancer and diabetes. In case of viral infection, it shows synergistic actions with antiviral drugs. Its anticancer action is due to antioxidant action, inhibition of hexsosamine pathway, and proappoptotic action. Anti-diabetic action is due to increase glucose uptake and beta cells protective action. It is also useful in CNS disorders. Resveratrol also shows anti-aging action. Extensive preclinical studies have been completed more clinical research should be carried out to establish as a lead compound.
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