Furosemide in Acute Kidney Injury – A Vexed Issue

Loop diuretics have been traditionally used to enhance renal excretion of excess salt and water. Loop diuretics have numerous reno-protective properties that may help improve the management of Acute kidney injury and subsequently patient outcomes. Given the improved prognosis of non-oliguric acute kidney injury, it may be tempting to use loop diuretics in oliguric acute kidney injury to improve the urine output. A review of literature shows that the use of loop diuretics in patients with acute kidney injury has been associated with inconclusive results despite the theoretical benefits. Here we review the concerns pertaining to the use of furosemide in patients with Acute kidney injury.