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An Integrated Approach For Psoriatic Arthritis

Journal: Journal of Pharmacy Research (Vol.11, No. 6)

Publication Date:

Authors : ; ;

Page : 645-657

Keywords : Psoriatic arthritis Screening tools new concepts on genotype and phenotype relationships Conventional treatments new agents used for psoriatic arthritis.;

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Psoriatic arthritis is a debilitating condition, which affects approximately the one-quarter of psoriasis patient. Psoriatic arthritis is a systemic, polymorphic joint disease with a variable presentation and clinical course. Psoriatic arthritis (PsA) is a systemic, polymorphic joint disease with the variable presentation and clinical course. The outcome depends upon the association with severe comorbidities such as diabetes, hypertension and dyslipidemia .This articles reviews about the recent advances done in psoriatic arthritis over a past several years with emphasis on early diagnosis for better understanding of pathogenesis and with new therapeutic approaches. There is lot of clinical laboratory and ultrasound features which help in identifying the patients destined to develop Psoriatic arthritis with the several screening tools which have been developed. It also recognized about the genetic and epigenetic factors, as well as T cells and cytokines, which plays a significant role in the pathogenesis of (PsA), and also several targets have been identified for therapeutic interventions. New therapies have been developed and also tested in Psoriatic arthritis and found to be highly effective for both skin and joint manifestations of the disease. The expectation is that, in future, Psoriatic arthritis patients can be treated early with more aggressively and that there will not be any significant progression of joint damage.

Last modified: 2017-06-27 16:30:21