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Review on Osteoporosis A Preventable and management disease in Relation to Diabetes

Journal: Journal of Pharmacy Research (Vol.11, No. 6)

Publication Date:

Authors : ; ; ; ;

Page : 753-761

Keywords : Calcium; Vitamin D; Osteoporosis; Neuropathy; Bisphosphonates.;

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Abstract

It is a chronic bone disease associated with poor bone remodeling and bone formation. Bone mass and changes in bone structure leads to increased risk of fracture. The pathological condition creates bones to become weak and fracture that commonly affects the parts of hip, wrist and spine. It consist of proteins, collagen, and calcium and associated substances confers the strength.The diabetes is a prolong metabolic disorder associated with multiple complications. The diabetes develop at younger age and suffering from neuropathy,vision problems may reduces the bone mass responsible for risk of bone fracture. The imbalance between osteoclast and osteoblast bone response through out the remodeling buildup the disease. The repeated events promotes bones to meet normal demands and falling more stress on bone advancing the risk of fracture. The diagnosis pattern can be suggested towards X-rays, various vital organ function test, pathological test towards the disease and confirmed by tests to measure bone density. It affects men and women in normal health care scenario. The risk factors include aging, low body weight, low sex hormones and menopause, smoking, alcohol, some medications will impact the development of disease. Current treatment address the medications like bisphosphonates, selective estrogen receptor modulators, calcium and vitamin D supplements. It is a healable disease that can results in devastating the physical, psychosocial, and economic consequences of the patients. The early recognition of the causes and risk factors medication therapy measures impact the outcomes.

Last modified: 2017-06-27 21:56:17