A case of idiopathic hypoparathyroidism with Systemic Lupus Erythematosus

Hypoparathyroidism is a rare disease. The main cause of hypoparathyroidism is postsurgical hypoparathyroidism. However, cases of hypoparathyroidism in patients suffering from SLE exist although it is uncommon. We present the case of a woman suffering both from systemic lupus erythematosus and hypoparathyroidism. This reported association of hypoparathyroidism with lupus expands the spectrum of endocrine disorders seen in this disease. We suggest that there may be a common underlying pathophysiological process linking these diseases. Case report: We present a case of 50-year-old female resident of Madhya Pradesh, India who had chief complaint of seizures and generalised weakness. She is a known case hypothyroidism and systemic lupus erythematous for 15 years. Past history of repeated pericardial effusion. On admission, radiological findings on MRI (plain & contrast) were multiple lacunar infarcts in basal ganglia on both side and calcification in caudate nucleus, putamen, pulviener, internal capsule. Laboratory findings were total serum calcium – 4.5mg/dl, PTH – 2.02pg/ml, ionized calcium – 0.67mg/dL, 25-hydroxy vitamin-D – 70ng/ml. Hypercaliuria present. ANA; positive, Anti-ds DNA antibodies positive. All other laboratory findings are within normal limit. This association of hypoparathyroidism with SLE is a rare association.