PTEROCARPUS MARSUPIUM EXTRACTION AND EVALUATION FOR DIABETIC NEUROPATHY

Herbal medicines are considered to offer gentle means of managing chronic diseases at a lower cost. Traditional Medicines derived from medicinal plants are used by about 60% of the world's population. Diabetes is an important human ailment afflicting many from various walks of life in different countries. In India it is proving to be a major health problem, especially in the urban areas. Pterocarpus marsupium. (PM) heartwood and bark have been majorly used as antidiabetic remedies in many cultures for thousands of years. The aim of this research is to address the existing evidence on antidiabetic Neuropathy effects of the P. marsupium by tail flick method and Eddy's hot plate method by Thermal hypoalgesia. In this research work , Experimental Study Design for Diabetic neuropathy screening the animals were divided into Group-I: Rats served as normal control group. Group-II: served as diabetic/disease control. Group-III: Diabetic rats treated with PM , at a dose 50mg/kg (low dose).GroupIV: Diabetic rats treated with PM at a dose of 100mg/kg (high dose). Group V: Diabetic rats treated with Diclofenac sodium (standard drug) at 100mg/kg. Diabetic neuropathy alterations were tested using thermal hypoalgesia and Tail flick responses. By the results Pterocarpus Marsupium is having Neuro protective activity in diabetic animals. Keywords: Anti diabetic neuropathy, Pterocarpus marsupium, Standard drug, Tail flick method, thermal hypoalgesia method