DOWLING DEGOS DISEASE WITH RETICULATE ACROPIGMENTATION OF KITAMURA A CASE REPORT

Abstract : INTRODUCTION Dowling Degos Disease (DDD) and Reticulate Acropigmentation of Kitamura (RAPK) are rare autosommal dominant disorders. In DDD heavily pigmented macules are arranged in a reticular pattern with a tendency to coalesce on flexural skin. Extensive areas of skin may be affected. RAPK presents as slightly depressed hyperpigmented macules on dorsa of hands and feet that evolve into a reticulate pattern. Palmoplantar pits may be associated with RAPK.CASE REPORT A 40 year old female presented with hyperpigmented macules for 10 years. Family history of similar lesions was present. Dermatological examination revealed hyperpigmented macules on limbs, trunk and thighs, axilla, neck, groin, more pronounced over flexures with reticulate pattern in certain areas. Patient also had pitting of palms and soles. Biopsy taken from hyperpigmented macule had features consistent with DDD.DISCUSSION DDD and RAPK diseases may appear together supporting the concept that they aredifferent expressions of one disorder. Other cutaneous findings of DDD include perioral scars, comedo like papules, hidradenitis suppurativa, keratoacanthoma, multiple cysts and abscesses. RAPK can be associated with palmoplantar keratoderma, acrokeratoelastodosis, alopecia areata, nevus spilus, nevus anaemicus and bilateral talipes. CONCLUSION This case is presented for rare the association of DDD and RAPK.