Serum Levels of AST and ALT Enzymes and Proteins in Boilers Infected with AFB1

The fungal exudates of Aspergillus flavus is known as Aflotoxins in which Aflotoxin B1 (AFB1) is prominent having a broad spectrum of lethal impact as carcinogenic, hepatotoxic, mutagenic, and nephrotoxic agent . The toxic effect of AFB1 varies differently in different age, sex, breed and immuno status of birds .Consumption of low amounts of Aflotoxins for a long period may result in decrease of weight gain, poor feed effiency, increased susceptibility to diseases, and broodiness in layers. Acute and chronic renal failure is the most disastrous effect. Our present investigation is focused on determining the levels of AST and ALT enzymes and serum proteins in broilers one week old suffering during chronic Aflotoxicosis. ).Two groups (A, B,) of broilers of one week old were intubated with various doses of AFB1 orally. Broilers were necropsied at 1, 3, 8 and 11 days of infection and blood samples were collected and analyzed for AST and ALT levels.