ResearchBib Share Your Research, Maximize Your Social Impacts
Sign for Notice Everyday Sign up >> Login

Syntheses and Characterizations of Some New N-alkyl, Isoxazole and Dioxazole Derivatives of 5-Chloroisatin

Journal: International Journal of Advanced engineering, Management and Science (Vol.3, No. 8)

Publication Date:

Authors : ; ; ; ;

Page : 882-885

Keywords : 1; 3-dipolar cycloaddition; 4-Chlorobenzaldoxime N-alkylation; 1H NMR; 13C NMR;

Source : Downloadexternal Find it from : Google Scholarexternal


N-alkyl and cycloadducts derivatives of 5-Chloroisatin were synthesized in good to excellent yields. The method evidences a selective N-alkylation when using 1,2-bis (2-chloroethoxy) ethane as efficient spacer at room temperature on the 5-Chloroisatin moiety. A general method for the 1,3-dipolar cycloaddition of 4-Chlorobenzaldoxime to alkynes provides a useful alternative route to get newisoxazole et dioxazole derivatives.

Last modified: 2017-09-07 02:41:06