The puzzle of new etiological agents in the Americas: Punta del Toro virus another piece?

In a recent study of undifferentiated tropical fevers in an endemic area of Colombia, it was shown that not all acute fevers are caused by the dengue virus (1). The complex clinical-epidemiological panorama of tropical fevers has become a puzzle of difficult resolution due to the appearance of new etiological agents in the Americas such as Chikungunya and Zika. For the differential diagnosis Hantavirus, Arenavirus, Orupuche, tick thrombocytopenic virus, Heartland virus, leptospira and malaria should be considered.