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Toxic Epidermal Necrolysis (TEN) Induced by a Combination of Phenytoin and Oxcarbazepine

Journal: Austin Pediatrics (Vol.3, No. 2)

Publication Date:

Authors : ; ;

Page : 1-3

Keywords : Toxic Epidermal Necrolysis; Oxcarbazepine; Phenytoin;

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Toxic Epidermal Necrolysis (TEN) or Lyell syndrome is an acute systemic inflammation that involves skin, mucous membranes, respiratory epithelia and intestinal. It is regarded as final stage of Stevens - Johnson syndrome (SJS); both entities are part of same pathophysiological and immunological process, differing only by extent of the body surface (BS) area affected. We report an 8 years old female which present a severe phenytoin and oxcarbazepine adverse reaction coursing with all clinical stages of SJS-TEN responding favorably to treatment with intravenous immunoglobulin (IGIV), without use of steroids.

Last modified: 2017-10-05 17:20:23