ASSESSMENT OF HEALTH RELATED QUALITY OF LIFE IN POLY CYSTIC OVARIAN SYNDROME PATIENTS AND FACTORS AFFECTING OVARIAN FOLLICULAR SIZE

Polycystic ovarian syndrome (PCOS) is defined as the presence of hyperandrogenism (clinically and/or biochemically) chronic anovulation in the absence of specific adrenal pituitary gland abnormality. The clinical features of PCOS are Hyperandrogens, Hirsutism, Acne, Obesity, Insulin resistance. The impact of these symptoms on a woman quality of life may be profound and can results in psychological distress that threatens her feminine identity. The study shows factors impacting quality of life in women. It has been measured by using chi-PCOSQ (Chinese PCOS Questionnaire) Likert scale. PCOS quality of life assessment is demonstrated by 1- 7 point likert scale. Amongst all domains impairment was seen in infertility domain followed by menstrual irregularity, acne, and hair loss. Spontaneous abortions were found to be frequent in PCOS patients whose BMI range is above normal. In present study of assessing Quality of life, treatment with metformin shows effective results in overweight and obese patients. Clomiphene citrate and inositol are highly effective in non-obese and underweight patients. Keywords: Quality of life, HRQoL (Health related quality of life), PCOS (Polycystic Ovarian Syndrome), Clomiphene citrate, Metformin.