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SYNTHESIS OF 3-[4-AMINO-N-SUBSTITUTED-o-ANISAMIDO- 5-YL]AMINO-5-SUBSTITUTED-1,2,4-DITHIAZOLE

Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.04, No. 10)

Publication Date:

Authors : ;

Page : 3890-3894

Keywords : 3-{4-Amino-N-[2-(dithethylamino)ethyl-o-anisamido-5-yl}amino-5-substituted -imino-1; 2; 4-dithiazole; 4- amino-5-substituteddithiobiureto-N-[2-(dithethylamino)ethyl-o-anisamide; Bromine in Chloroform.;

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Abstract

A novel series of 3-{4-Amino-N-[2-(dithethylamino)ethyl-o-anisamido-5-yl}amino-5-substitutedimino-1,2,4- dithiazole was synthesized by the oxidative cyclization of 4-amino-5-substituteddithiobiureto-N-[2- (dithethylamino)ethyl-o-anisamide in chloroform medium by making the use of liquid bromine as oxidizing agent. The products were characterized and justified on the basis of elemental analysis, chemical characteristics and spectral studies. Keywords:3-{4-Amino-N-[2-(dithethylamino)ethyl-o-anisamido-5-yl}amino-5-substituted -imino-1,2,4-dithiazole, 4- amino-5-substituteddithiobiureto-N-[2-(dithethylamino)ethyl-o-anisamide, Bromine in Chloroform.

Last modified: 2017-10-24 20:45:02