Risk factors, cardiohemodynamics and renal function state in patients with chronic heart failure and myocardial infarction in anamnesis

The importance of the problem of heart failure for modern medicine is due to its growing prevalence and poor prognosis, despite a tendency to decrease of deaths from major cardiovascular diseases: coronary heart disease (CHD) and arterial hypertension (AH). Objective: to evaluate the risk factors, the state of cardiac hemodynamics and kidney function in patients with chronic heart failure (CHF) and acute myocardial infarction (AMI) in history. A retrospective analysis of 144 case histories of patients with CHF with preserved systolic function, aged 40 to 80 years and with disease duration from 1 year to 10 years was made. The patients were divided into 2 groups depending on the presence of anamnestic data in favor of past AMI: group 1 – 35 patients (24%) with CHF and AMI in anamnesis, 2 group, 109 patients (75,7%) with CHF without AMI in anamnesis. It was found that prevalence and severity of hypertension as well as arrhythmia were not significantly different in patients of both age groups. Among patients with stable angina and CHF with preserved ejection fraction there was established a high prevalence of hypertension, diabetes and obesity. The presence of AMI in anamnesis was associated with worse control of hypertension on the background of normal indicators of lipidogram, compared to patients with CHF without AMI in anamnesis. There was established a higher incidence of revealing patients with impaired renal function among patients with CHF with a trend to increase of manifestations of chronic renal failure and hyperuricemia among patients with postinfarction cardiosclerosis, regardless of patients' age.