ANTIBACTERIAL ACTIVITY OF SECONDARY METABOLITES FROM MARINE SPONGE (CLATHRIA INDICA) ASSOCIATED BACTERIA

Objective: To isolate the potential bioactive secondary metabolites producing bacteria associated with Clathria indica from Thondi, Tamil Nadu. Methods: Ethyl acetate extraction method was used to extract the secondary metabolites and antimicrobial assays was carried out. Results: Three potential strains were highly active in test pathogens. The extracted secondary metabolites were used to MIC and MBC test. Conclusion: Based on the present study MSB11 secondary metabolites can be effective bioactive drug against clinical pathogens. Keywords: secondary metabolites, Clathria indica, MSB11 strain, clinical pathogens, MIC and MBC