CASTLEMAN'S DISEASE- A RARE ENTITY

Castleman's disease is a lymphoma-like disorder which can present as a localised or generalised lymphadenopathy, along with systemic symptoms. It is postulated to be associated with HHV 8 virus.We present to you a case of Castleman's disease, who presented to us with abdominal distension and lymphadenopathy involving supraclavicular and axillary nodes. On examination, patient had pallor and multiple supraclavicular, axillary and inguinal nodes enlarged. Investigations revealed anemia, relative lymphocytosis with normal renal and liver function tests. Imaging studies revealed a right side pleural effusion and ascites. Histopathology of lymph node specimen showed angiolymphoid follicular hyperplasia, suggestive of Castleman's disease supported by immunohistochemistry.