ISOLATION AND CHARACTERIZATION OF NATURAL COMPOUNDS FROM LIQUORICE

The present research work is mainly concened with the natural compounds that are obtained from traditional medicinal plants. There are number of natural compounds have been available in the nature. Some natural compounds are very useful to human being and have life pontential to save human from many uncurable disease. Keeping view in the mind the research is focused to extract and isolate antioxidant, anti-inflammatory, anticancer, antihyperlipidmic, antidiabetic, antiulcer activites containing compounds are studied. The major natural compounds are liquorice, ginger, alliuam, triphala (harda, bahera, pipali, amla and guggulu). The glycyrrhyza glabra is obtained from rhizomes of liquorice and useful as expectorant and ulcer healing properties with carbenoloxolone as major constituents. All components are isolated from the concerned extracts. The extractions of all plants are based on successive solvent extraction method for all drugs. The constituents are confirmed by structure elucidation. The structure of each compounds are intrepereted by different spectral techniques like Infrared spectrum, nuclear magnetic spectrum (hydrogen anc carbon thirteen spectra) and mass spectroscopy for molecural formula and molecular weight of the unknown compounds. Key words: Liquorice, extraction and chromatography