Effect of aqueous extract of Ecbolium viride on thioacetamide induced liver cirrhosis in albino Rat

The present experiment has been designed to check hepatoprotective activity of aqueous extract of Ecbolium viride in albino rat. The whole plant aqueous extract was used for treatment. The thioacetamide was used for induction of liver cirrhosis. For this work rats were divided into control group, thioacetamide induced group and E. viride treated group. The thioacetamide induced toxicity in albino rat was established by the significant increase in total bilirubin, direct bilirubin; SGOT and SGPT while significant decrease in liver protein. The treatment of E. viride resulted into remarkable decrease in total bilirubin, direct bilirubin; SGOT and SGPT while significant increase in liver proteins as compared to the thioacetamide induced group indicating its hepatoprotective activity.