STUDY OF ANTIDIABETIC DRUGS PRACTICE IN INPATIENTS AND OUTPATIENTS OF BOLAN MEDICAL COMPLEX HOSPITAL AND SANDEMAN PROVINCIAL HOSPITAL QUETTA BALOCHISTAN

Diabetes mellitus usually referred to as diabetes, it is a group of metabolic disorders in which there are high blood glucose levels over a prolonged period. These symptoms include of high blood sugar frequent urination, increased hunger, and increased thirst. The present study was carried out to assess antidiabetic drugs practice and general tendency of diabetes among patients at two major Hospitals namely Bolan Medical Complex Hospital Quetta and Sandeman Provincial Hospital Quetta, for achievement of comparison results for good glycemic control in diabetic patients. In this regard the data was collected in the form of Prescriptions and complete records of diabetic patients including inpatient treatment charts which were monitored and data was followed as per WHO prescription proforma. The study revealed that inpatient charts of BMCH were contain Insulin (88%), Metformin (14%), Glimepiride (3%), Gliclazide (1%) and combination drugs Sitagliptin and Metformin (3%), Glibenclamide and Metformin (2%) where as the SPH inpatient charts were containing the drug insulin (85%), Metformin (8%), Glimepiride (4%), Pioglitazone (3%), Sexagliptin (1%), Gliclazide (1%), Glibenclamide (1%) and combination drugs Sitagliptin and Metformin (3%), Glibenclamide and Metformin (3%) furthermore the study found that in case of BMCH outpatients drugs were including Metformin (75%), Glibenclamide (20%), Gliclazide (19%), Glimepiride (17%), Insulin (15%), Sitagliptin (7.80%) where as the combination drugs prescribed Glibenclamide and Metformin (2%), Sitagliptin and Metformin (2%) and Pioglitazone and Glimepiride (1%) were found to be maximum among several available antidiabetic drugs. Category wise the maximum prescribed drugs in inpatients were almost Insulin (88%) Metformin (14%, biguanide) Glimepiride (8%, Sulfonylurea category), and (Pioglitazone 4%, Glitazone category). Sexagliptin and Gliclazide was prescribed very less (1%). Study found that the disease which was very common among diabetic inpatients was hypertension (58%). In age groups the highest prevalence in inpatients of BMCH and SPH was same 51 to 60 and BMCH outpatients were found in the age of 41 to 50. Women patients (54.44%) were found to be predominate over Men patients (46.64%).Present study also showed that the number of patients were more with type ll diabetes than the patients with type l, and most of the patients were diagnosed with diabetic foot. Keywords: Diabetes Mellitus, inpatient, outpatient, antidiabetic drugs.