A Rare Presentation of Extra Pulmonary Small Cell Carcinoma at Tongue

Context: To report a case of extrapulmonary small cell carcinoma at a rare site of tongue with excellent prognosis with standard therapy. Case: A 65-year-old previously healthy male presented initially with difficulty in swallowing and later, with a solitary neck lump and he was diagnosed as extrapulmonary small cell carcinoma of tongue. Unlike small cell carcinoma lung, extrapulmonary small cell carcinoma is uncommon and in base of tongue, it is extremely rare. Cisplatin (75 mg/m2) and Etoposide (100 mg/m2) were administered in combination at 3 weeks interval as neoadjuvant chemotherapy for 3 cycles, as well as concomitant chemotherapy for 3 cycles with external beam radiation in a dose of 64 Gy. The patient tolerated well the treatment. Conclusion: The prognosis of extrapulmonary small cell carcinoma is felt to be extremely poor. Contrary to other reports, this case demonstrates that a good response with standard therapy is possible.