ANTIOXIDANT AND ANTIDIABETIC PROPERTIES OF VARIOUS EXTRACTS OF BERBERIS ARISTATA

Formation of free radicals in the human body is a daily process and in the present set up of life there occurs inclination in the formation of free radicals in every human body because of life style change. The over production and the accumulation of free radicals leads to the generation of various types of diseases like, diabetes, Cancer, Alzheimer etc. Also in the present age the most dreadful and drastic disease viz diabetes had touched the heights as most of the humans above the age of 40 had affected by the concerned disease. Various types of nourishments are being taken against the free radicals and various types of allopathic medicines are taken against the diabetes, but none finds the complete effect neither against the complete neutralization of free radicals nor against the diabetes. So Scientists finally showed their interest towards the utilisation of phytochemicals or medicinal plants as a whole. So taking these factors into consideration the study in reference have been carried out. Berberis aristata have been collected from the Kishtwar region of Jammu and Kashmir. The plant extracts have been analysed for the antioxidant and antidiabetic properties. All the plant extracts have been found effective against the inhibition of free radicals, and the inhibition of alpha amylase and alpha glycosidase enzymes. Among the carious extracts of the plant, the acetone extracts have been found much effective against the diabetes and also the antioxidant power of the acetone extract of plant have been found to be much more effective than the water and DCM extracts. Keywords: Antidiabetic, antioxidant, Berberis aristata, Plant extracts, DPPH, Acarbose