Characterization of Curcumin Encapsulation in Chitosan-Sodium Citrate Nanoparticles

The encapsulation of curcumin in chitosan-sodium citrate nanoparticle was studied with ionic gelation method. Identification of functional groups was determined by Fourier Transform Infrared spectrophotometry method. The crystallinity characteristic was tested by X-Ray Diffraction (XRD). Particle size determination was performed using Transmission Electron Microscopy, whereas the morphological characterization was tested by Scanning Electron Microscopy. The results showed that the electrostatic interaction between the amine group and a carboxyl group could cause a shift in the uptake of chitosan-sodium citrate nanoparticles at wave number 1635 cm-1 to 1581 cm-1. Qualitative data of XRD spectra showed that there reduced crystallinity of curcumin. Nanoparticles had a size of ±95nm.