The Skin: A Mirror Reflecting Neuro-Psychiatric Disorders

Actually doctors of all clinical specialties understand that the skin is a mirror of many diseases as celiac diseases, polyposis syndromes, and intestinal malignancies. And, as GI diseases can have a dermatological manifestation, GI tract can be involved in many dermatological disorders as vesicobullous disorders[1,7,8,12]. Skin also mirrors bone marrow[6,16] and reflect some malignancies[14]. Immunological and rheumatic diseases could also show signs on our skin[10-11]. Diabetes mellitus is a major health problem in Gulf countries. Muco-cutaneous lesions are associated with diabetes. Skin manifestation of diabetes should be common to be missed by practioners. They can take credit for both detecting DM and facilitating early diagnosis of its complications[2]. Moreover, researchers studied the role of certain neuro-transmitters on skin which is also the mirror of souls[5-9]. The mammalian skin is both a site for the production of and a target for bioregulation by serotonin (5-HT). General practitioners, dermatologists, and psychiatrists should be alert to a some skin lesions common with patients on antidepressants with the indication of their clinical monitoring and management[17-18].