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Acute psychosis induced by topiramate

Journal: International Journal of Basic & Clinical Pharmacology (Vol.3, No. 2)

Publication Date:

Authors : ;

Page : 405-407

Keywords : Topiramate; Mania Rating Scale; Brief Psychiatric Rating Scale; Drug? drug interaction; CYP450;

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Topiramate (TPM) is a new potent antiepileptic drug (AED) used as add-on therapy for generalized and partial seizures that are resistant to the other AEDs; or as a mood stabilizer, and for reducing weight gain associated with olanzapine and clozapine in patients with bipolar disorder or schizophrenia. However, there is a higher risk of psychosis with TPM in patients with a past history of psychiatric disorder. This case report highlights emergence of psychosis that was related to TPM which resolved on discontinuation. [Int J Basic Clin Pharmacol 2014; 3(2.000): 405-407]

Last modified: 2014-04-01 23:05:55