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CYTOTOXIC EFFECT OF LOW MOLECULAR WEIGHT PROTEIN ISOLATED FROM CROTALARIA PALLIDA

Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.05, No. 01)

Publication Date:

Authors : ; ;

Page : 124-129

Keywords : Low Molecular weight proteins; SDS-PAGE; apoptosis; antitumor agent; Crotalaria pallida.;

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Abstract

Low molecular weight proteins (LMWPs) were isolated from Crotalaria pallida using Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE). The antimitotic assay has been investigated using onion root tips whereas apoptosis assay was conducted on MCF-7 cell lines. A 14 kDa protein has been identified as potent antitumor agent. Key words: Low Molecular weight proteins, SDS-PAGE, apoptosis, antitumor agent, Crotalaria pallida

Last modified: 2018-01-08 19:59:48