BIOACTIVE POTENTIAL AND ANTIOXIDANT STATUS OF LABORATORY GROWN Calocybe indica (MILKY MUSHROOM)

Calocybe indica (Milky mushroom) is one of the easily available and culturable mushrooms at relatively low cost. It comprises economic source of protein enriched with antioxidants and immune enhancing factors required for human health. Medicinal property of C. indica is due to the presence of polysaccharides, proteins, aminoacids, terpenes, terpenoids and phenols. In this study, methanolic extract of C.indica was used for invitro antioxidant, Protein denaturation inhibition, Nitric oxide scavenging and Membrane stabilization assays. Total Antioxidant activity (TAA) and phenolic content of Laboratory grown C. indica by phosphomolybdenum method was equivalent to that of ascorbic acid. Antiinflammatory effect was estimated by protein denaturation inhibition assay exhibits inhibition of 66.80 % at 1000 µg/ml. C.indica also found to possess nitric oxide scavenging activity capable of 69.76 % inhibition at 1000 µg/ml. Membrane stabilization assay revealed that methanolic extract of C.indica provides 55.83 % membrane stabilization. Key words: C. indica, Antioxidant, Antiinflammatory, Nitric oxide, Membrane stabilization