PREVELANCE OF INFECTION IN DAIBETIC CHILDREN WITH H. PYLORI BACTERIA AND RISK FACTORS OF H. PYLORI IN DIABETIC CHILDRENJournal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.05, No. 04)
Publication Date: 2018-04-09
Authors : Tenveer Ahmed Sibghat Ullah Khan Dr Bakht Zia;
Page : 2306-2308
Keywords : Helicobacter pylori; Diabetes Mellitus; Breath Urea test.;
Objective: To evaluate the infection in diabetes mellitus cases with Helicobacter pylori. Introduction: It has been reported that the H. pylori infection prevalence high in patients of diabetes mellitus. Place and Duration: In the pediatric department of Services Hospital, Lahore for the period of 6 months from 1st of July 2016 to 31st of December 2016 under the supervision of ethical committee. Patients and methods: This case-control study was in the pediatric department of Services Hospital, Lahore for the period of 6 months from 1st of July 2016 to 31st of December 2016 Diabetes mellitus (twice fasting blood glucose> 126 mg / dL, blood glucose> 200 mg / dL or diabetic clinical indication) was included in this study for 2 months, regardless of the duration of the illness without antibiotic therapy history. Breath urea test (UBT) was performed with ISOMAX 2000, manufactured by Canada. Forty-eight cases (M: 28, F: 21) were tested for urea breathing to detect H. pylori infection. In addition, 100 healthy controls were selected. The urea breath test was also performed at all of the children's controls. Chi-square test was used for analysis with SPSS version 10.0. Results: Forty eight cases with a mean age of work of 8.1 ± 2.6 (range 3.5-15) were included. Positive UBT test was performed in 14 (28.6%) and positive UBT in 30 (27.8%) of 108 control groups (P value> 0.05). Conclusion: Diabetic children are not at risk for high H. pylori infection, but a study with a large sample size is needed. Keywords: Helicobacter pylori, Diabetes Mellitus, Breath Urea test.
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