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Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.05, No. 04)

Publication Date:

Authors : ;

Page : 3062-3065

Keywords : Diabetic Foot. Diabetes Mellitus; Amputations. Glycemic Control; Complications of Diabetes Mellitus.;

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Objective: To association of hypertension, treatment modality and socioeconomic status with lower extremity amputation in persons with diabetes mellitus. Methods: 100 patients fulfilling the inclusion criteria were recruited. %0 of them were controls and 50 of them were cases with amputation caused by diabetic lesions, admitted for treatment in the Department of Surgery for care of Diabetes Mellitus. Various treatment modalities, hypertension, and socioeconomic background were evaluated among controls and cases according to a pre-designed questionnaire during period from August, 2017 to March, 2018. Demographic data was gathered from the respondents. Frequency tables were generated regarding research variables. Results: 100 participants were interviewed about the treatment they used, hypertensive control and socioeconomic background in association with diabetic foot. Patients were allocated to either cases or control group, based on whether they had an amputation or not. There was slight male dominance in both cases and controls with males contribution 68% and 70% to sample respectively. Predominant fractions of patients' were of age greater than 50 years. 64% of samples were from low socioeconomic background in cases, whereas among controls 74% of patients were on middle class background. Equal fraction of cases and controls had hypertension. Among cases, 58% were using oral hypoglycemics, 72% were using Insulin and 16% had taken homeopathic medications. The proportion of oral hypoglycemics, insulin and homeopathic medications were 68%, 60% and 14% among controls. Age and Hypertension did not showed any significant risk association, same holds true for gender, whereas socioeconomic background had a strong risk association with amputation. None of the treatment pattern, whether oral hypoglycemic drugs, Insulin or homeopathic medication showed any significant risk association Conclusion: Age, hypertension and medicines used failed to show any significant association with development of diabetic ulcers, leading to amputation. Whereas lower socioeconomic status had a stronger risk association with development of Diabetic Amputation. Key Words: Diabetic Foot. Diabetes Mellitus, Amputations. Glycemic Control, Complications of Diabetes Mellitus.

Last modified: 2018-05-07 00:58:02