INTERLEUKIN-6 LEVELS IN ANGINA PECTORIS

Objective; To determine the frequency of raised Interleukin-6 level in cases presenting with angina pectoris. Methodology; This cross sectional study was conducted at Sheikh Zayed Hospital, Lahore during January to August 2017. In this study the cases with age range of 30 years or more of both genders were included. Angina pectoris was labelled as yes when there was typical central chest pain lasting for less than 30 minutes with or without ST-T changes on ECG and normal cardiac enzymes. The cases end stage liver or renal diseases were excluded. Then the blood of these cases was sent for IL-6 level. The value > 5 ng/ml was labelled as raised. Results; In this study 200 cases of angina pectoris were included having, 112 (56%) males and 88 (44%) females. The mean age of the cases was 52.78±6.82years and mean IL-6 levels were 25.58±8.18. Raised IL-6 levels were observed in 120 (60%) cases. There was no significant difference regarding age groups with p= 0.71. Raised IL-6 levels were seen in 32 (80%) of cases with p= 0.001 and similarly in cases with DM affecting 36 (66.67%) cases with p= 0.04. Conclusion; Raised Interleukin-6 level are not uncommon in angina pectoris and it is significantly high in cases of DM, HTN. Key words; Angina Pectoris, IL-6 levels, HTN, DM