MECHANISTICALLY CATIONIC MICELLAR CATALYSIS ON THE HYDROLYSIS OF MONO 2,5-DI METHOXY PHENYL PHOSPHORAMIDE

Hydrolysis of mono- 2,5-dimethoxy phenyl phosphoramide (mono-2,5-DMPP) was studied in micellar solutions of cetyltrimethylammonium bromide (CTABr) at pH-9.0. The hydrolysis followed first order kinetics with respect to mono-2,5DMPP concentration. At the concentration of critical micelle concentration (CMC) the rate of hydrolysis increased with increasing CTABr concentration. The binding constant of micelle for mono-2,5-DMPP and the rate constant in micellar pseudo phase were determined from kinetic data using the pseudo phase model.