EFFECT OF POORANACHANDIRODAYAM ON COLON CANCER CELL LINES

Colon cancer is the major cause of death worldwide. Pooranachandirodayam is a herbo-mineral siddha preparation used to treat chronic ailments. This study was conducted to elucidate the efficacy and probable underlying mechanism of Pooranachandirodayam in colon cancer using in vitro studies. But Pooranachandirodayam had solubility issues with the methods earlier described for in vitro studies and with different concentrations of other varying solvents. From the results of the in vitro studies, PC shows no effect on the colon cancer cells, which may be due to the inappropriate vehicle used. Keywords: Colorectal cancer - Pooranachandirodayam – solubilisation – in vitro studies