Myristica Fragrans (MF): Potential Role as an Antioxidant and Anti-Inflammatory Agent

The aim of the present study was to evaluate anti- inflammatory and antioxidant potential of Myristica fragrans (MF) in albino rabbits. Rabbits were divided into four groups of six each, depending on the diet received Group I: Normal control rabbits, Group II: (MF group), Group III: (HFD group), Group IV: (HFD with MF group). Blood samples were collected from the marginal vein of pinna of overnight fasted rabbits at the end of experimental period for estimation of Malondialdehyde (MDA), Reduced glutathione (GSH) and Vitamin C. Significant anti-inflammatory and anti-lipid peroxidative effect was observed in animals who received supplementation of Myristica fragrans along with high fat diet induced oxidative stress. Statistically significant increase in antioxidant parameters (Vit C, GSH) was observed with Myristica fragrans supplementation. The results suggest the antioxidant and anti inflammatory activity possessed by nutmeg could be helpful in preventing or slowing the progress of various oxidative stress-related diseases and inflammatory diseases.