SERUM INTERLEUKIN 6 LEVEL AND ITS ROLE IN PREDICTING ANGINA PECTORIS RISK

Objective: To determine the association between serum interleukin 6 levels and angina pectoris. Methodology: The cross sectional study was conducted at Sheikh Zayd Hospital, Lahore during February to September 2016. 40 to 60 years old diagnosed cases of angina pectoris, either males or females were added in the study population. The criteria was normal ECG waves at rest and normal cardiac enzymes level. IL-6 levels were measured in patients by collecting 3ml blood sample. More than 5ng/ml was normal level. Results: 100 angina patients were enrolled. Male to female ratio was 58 and 42 each, respectively. Mean age group was 54.29.3 years. 68 individuals had raised IL6 levels. No association between gender and IL- 6 level was noticed. However the level was higher in individuals with diabetes mellitus and hypertension, affecting 20 and 22 cases in each group. P value was 0.01 and 0.05 respectively, which was statistically significant. Conclusion: IL-6 level was raised in patients with angina pectoris, its level was significantly raised in patients with DM and hypertension. Key Words: Interleukin 6, Angina pectoris, diabetes mellitus, hypertension.