IMPACT OF CHRONIC HBV INFECTION ON OUTCOMES OF ESR, SGPT AND IMPORTANT PARAMETERS OF CBC AMONG HBV INFECTED PATIENTS

Chronic hepatitis B virus (HBV) and chronic hepatitis C virus (HCV)infections remain one of the leading causes of chronic liver disease and hepatocellular carcinoma. Healthcare initiatives for chronic viral hepatitis to facilitate early diagnosis and linkage to care in an effort to reduce inpatient resource utilization associated with late diagnosis and end-stage liver disease have been partially successful (Cholankeril et al., 2016), The study population consisted of 50 patients (76.00 % male and 24.00 % were female). Our objective was to observe the impact of chronic HBV infections on ESR, SGPT and important parameters of CBC. This study examined the predominance of anemia (less RBC and hemoglobin), ESR and random blood sugar (RBS) in HBV infected patients. Along with anemia, ESR and RBS other blood related parameters such as WBC, neutrophils, lymphocytes, monocytes and eosinophils count were analyzed. Total WBC count was found significantly higher (male 42.10% and female 50.00%). Differential count of WBCs such as Neutrophils were found significantly associated with HBV positive individuals in both male (55.26%) and female (58.33%), Monocytes counts were found within the standard limit for 100.00% male and 100.00% female, lymphocytes counts were found normal for approximately 100.00% patients; and eosinophils counts were found mildly higher in both sexes (male 21.05%, female 25.00%) associated with HBV positive individuals. Platelets count found absolutely normal in both the sexes. HBV positive individuals had developed anemia in respect to RBC in male (65.79%) and female (50.00%) patients. Here it was found that 10.53% male and 75% female HBV patients suffer from anemia due to less hemoglobin content. Female patients number were very few for this reason it is very difficult to get the exact scenario regarding hemoglobin content. Female hemoglobin content may decrease due to menstrual cycle. The prevalence of high ESR was found in HBV infected patients examined. 57.90% male and 50.00% female HBV patients suffer high ESR, RBS level found mildly increase in both the sexes (male 10.53%, female 33.33%); and finally 39.47% male and 25.00% female were found with higher SGPT